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Generic Tadalafil (tadalafil) is an oral drug that is used to treat impotence (the inability to attain or maintain a penile erection). It is a phosphodiesterase inhibitor that is similar to sildenafil (Sildenafil Citrate) and vardenafil (Levitra).

Tadalafil (Tadalafil) prevents an enzyme called phosphodiesterase-5 from destroying cGMP so that cGMP persists longer. The longer cGMP persists, the more prolonged the engorgement of the penis.

Penile erection is caused by the engorgement of the penis with blood. This engorgement occurs when the blood vessels delivering blood to the penis increase in size and increase the delivery of blood to the penis. At the same time, the blood vessels carrying blood away from the penis decrease in size and decrease the removal of blood from the penis. Sexual stimulation that leads to the engorgement and erection causes the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase to produce cyclic guanosine monophosphate (cGMP). The cGMP is primarily responsible for increasing and decreasing the size of the blood vessels carrying blood to and from the penis, respectively.

Special information on Generic Tadalafil : Generic Tadalafil (Tadalafil) is not approved for use in pregnant women. Generic Tadalafil has not been evaluated in women who are breastfeeding.

The most common Tadalafil side effects are facial flushing (reddening), headaches, stomach upset, diarrhea, flu-like symptoms and nausea.

Tadalafil (Tadalafil) also may cause chest pain, low blood pressure, blurred vision and changes in color vision, abnormal ejaculation and priapism (prolonged and painful erection).

Tadalafil doses: For most individuals, the recommended starting Tadalafil dose is 10 mg per day taken before sexual activity. Depending on the adequacy of the response or side effects of Tadalafil, the Tadalafil dose may be increased to 20 mg or decreased to 5 mg a day.

The effect of Tadalafil may last up to 36 hours. Individuals who are taking medications that increase the blood levels of tadalafil should not exceed 10 mg in 72 hours (See drug interactions.)

 

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Generic Tadalafil (Tadalafil) is the first Erectile Dysfunction (ED) treatment that is effective up to 36 hours; the longest lasting among its kind. This allows you to choose the moment while spending time with your partner instead of rushing through with the act.

Generic Tadalafil (Tadalafil ) prevents an enzyme called phosphodiesterase-5 from destroying cGMP so that cGMP persists longer. The longer cGMP persists, the more prolonged the engorgement of the penis.

Generic Tadalafil (Tadalafil) pharmacokinetic parameters are what differentiate this agent from others within the class of PDE5 inhibitors. It is hypothesized that these pharmacokinetic differences may result in the following: improved PDE5 selectivity, faster onset of action, longer half-life, and lack of dosing restrictions (it can be taken without regard to food).

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